Michelle Garcia

  • Program Year: 1
  • Academic Institution: Dartmouth College
  • Field of Study: Theoretical/Computational Chemistry
  • Academic Advisor: Paul Robustelli
  • Practicum(s): Practicum Not Yet Completed
  • Degree(s):
    B.A. Chemistry, Pomona College, 2022

Summary of Research

Michelle Garcia is a graduate student at Dartmouth College studying theoretical and computational chemistry. She utilizes computer simulations to understand the mechanisms by which small molecule drugs bind intrinsically disordered proteins (IDPs), a challenging class of drug target associated with many currently untreatable neurodegenerative diseases and cancers. Michelle's research combines mathematical methods from topology and differential geometry with machine learning techniques to characterize IDP drug binding modes and inform the design of more potent inhibitors.


Garcia, M.; O'Leary, F.; O'Leary, D. Do-It-Yourself 5-Color 3D Printing of Molecular Orbitals and Electron Density Surfaces Journal of Chemical Education 2023 100 (4), 1648-1658
DOI: 10.1021/acs.jchemed.2c00907

Liu, Q.; Garcia, M.; Wang, S.; Chen, C.-W. Therapeutic Target Discovery Using High-Throughput Genetic Screens in Acute Myeloid Leukemia. Cells 2020, 9, 1888. https://doi.org/10.3390/cells9081888

Caltech Summer Research Presentations 2020



Academic Honors
Phi Beta Kappa, Amgen Scholar, Barry M. Goldwater Scholar, American Chemical Society Scholar

Academic Awards
Hispanic Scholarship Fund Scholar, QuestBridge Scholar, Zenith scholar, The Robert Rowan III (’68) Memorial Award in Chemistry