Mala Radhakrishnan

  • Program Years: 2004-2007
  • Academic Institution: Massachusetts Institute of Technology
  • Field of Study: Physical Chemistry
  • Academic Advisor: Bruce Tidor
  • Practicum(s):
    Lawrence Berkeley National Laboratory (2005)
  • Degree(s):
    Ph.D. Physical Chemistry, Massachusetts Institute of Technology, 2007
    A.B. Chemistry and Physics, Harvard University, 2000

Current Status

  • Status: Assistant Professor of Chemistry, Wellesley College
  • Research Area: Computational Drug and Biomolecular Design and Analysis
  • Publications

    Yingxin L. Zhang*, Mala L. Radhakrishnan*, Xiaohui H. Lu, Alec W. Gross, Bruce Tidor, and Harvey F. Lodish. Symmetric Signaling by an Asymmetric 1 Erythropoietin: 2 Erythropoietin Receptor Complex. Mol. Cell, 33:266-274, 2009.

    Patrick Flaherty, Mala L. Radhakrishnan, Tuan Dinh, Robert A. Rebres, Tamara I. Roach, Michael I. Jordan, and Adam P. Arkin. A Dual Receptor Crosstalk Model of G-Protein-Coupled Signal Transduction. PLOS Comp. Bio., 4:e1000185, 2008.

    Mala L. Radhakrishnan and Bruce Tidor. Optimal Drug Cocktail Design: Methods for Targeting Molecular Ensembles and Insights from Theoretical Model Systems. J. Chem. Inf. Model., 48:1055-1073, 2008.

    Mala L. Radhakrishnan and Bruce Tidor. Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment. J. Phys. Chem. B, 111:13419-13435, 2007.

    Mala L. Radhakrishnan and Sara L. Su. "Dead-End Elimination as a Heuristic for Min-Cut Image Segmentation", in IEEE Proceedings of the International Conference on Image Processing, 2006

    Jae Suk Ahn, Mala L Radhakrishnan, Marina Mapelli, Sungwoon Choi, Bruce Tidor, Gregory D. Cuny, Andrea Musacchio, Li-An Yeh, and Kenneth S. Kosik. "Defining Cdk5 Ligand Chemical Space with Small Molecule Inhibitors of Tau Phosphorylation", Chemistry and Biology, 2005, Vol. 12, 811-823


    Tao Deng, George Whitesides, Mala Radhakrishnan, Gary Zabow, Mara Prentiss. "Manipulation of Magnetic Microbeads in Suspension Using Micromagnetic Systems Fabricated with Soft Lithography." Applied Physics Letters 2001, 78, 12, 1775-1777.

    Yao-Yuan Chuang, Mala L. Radhakrishnan, Patton L. Fast, Christopher J. Cramer, and Donald G. Truhlar. "Direct Dynamics for Free Radical Kinetics in Solution: Solvent Effect on the Rate Constant for the Reaction of Methanol with Atomic Hydrogen", J. Phys. Chem. A 1999, 103, 4893-4909.

    Awards

    2008 DOE CSGF Howes Scholar
    Won honorable mention in DOE CSGF 2005 Essay Competition
    Dept. of Chemistry Award for Excellence in Teaching by a Graduate Student
    Robert T. Haslam Graduate Fellowhip, 2002-2003 (MIT)
    Phi Beta Kappa, 2000