Michael Mysinger

  • Program Years: 1996-2000
  • Academic Institution: Stanford University
  • Field of Study: Chemical Engineering and Quantum Chemistry
  • Academic Advisor: Charles Musgrave
  • Practicum(s):
    Sandia National Laboratories, California (1997)
  • Degree(s):
    Ph.D.. Pharmaceutical Sciences, UCSF, 2012
    M.S. Computer Science, Stanford University, 1999
    M.S. Chemical Engineering, Stanford University, 1996
    B.S. Mathematical Sciences, John Hopkins University, 1995
    B.S. Chemical Engineering, John Hopkins Universi

Current Status

  • Status: Scientist, Confometrx, Santa Clara, CA
  • Research Area: Molecular docking, solvation, GPCR structure-based discovery, Similarity Ensemble Approach (SEA)


6/12 Mysinger MM, Carchia M, Irwin JJ*, Shoichet BK* “Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking” Journal of Medicinal Chemistry, 55: 6582–6594.
5/12 Irwin JJ*, Sterling T, Mysinger MM, Bolstad ES, Coleman RG “ZINC: A Free Tool to Discover Chemistry for Biology” Journal of Chemical Information and Modeling, 52: 1757–1768.
2/12 Mysinger MM†, Weiss DR†, Ziarek JJ†, Gravel S, Doak AK, Karpiak J, Heveker N, Shoichet BK, Volkman BF “Structure-Based Ligand Discovery for the Protein-Protein Interface of Chemokine Receptor CXCR4” PNAS, 109: 5517–5522.
8/10 Mysinger MM, Shoichet BK* “Rapid Context-Dependent Ligand Desolvation in Molecular Docking” Journal of Chemical Information and Modeling, 50: 1561–1573.
8/09 Irwin JJ*, Shoichet BK, Mysinger MM, Huang N, Colizzi F, Wassam P and Cao Y “Automated Docking Screens: A Feasibility Study” Journal of Medicinal Chemistry, 52: 5712–5720.
1/02 Jones JP, Mysinger MM, and Korzekwa KR* “Computational Models for Cytochrome P450: A Predictive Electronic Model for Aromatic Oxidation and Hydrogen Atom Abstraction” Drug Metabolism and Disposition, 30: 7–12.
3/00 Widjaja J, Mysinger MM, Musgrave CB* “Ab initio Study of Adsorption and Decomposition of NH3 on Si(100)-(2x1)” Journal of Physical Chemistry B, 104: 2527–2533.


NIH Training Grant (2005-2006)
Computational Science Graduate Fellowship, Department of Energy (1996-2000)
Offered National Science Foundation Fellowship (1996)
Undergraduate Loy A. Wilkinson Award in Chemical Engineering (1995)
Undergraduate Mathematical Sciences Achievement Award (1995)