Irene Kaplow

  • Program Years: 2010-2014
  • Academic Institution: Stanford University
  • Field of Study: Computational Biology
  • Academic Advisor: Hunter Fraser
  • Practicum(s):
    Lawrence Berkeley National Laboratory (2011)
  • Degree(s):
    Ph.D. Computer Science, Stanford University, 2017
    M.S. Computer Science, Stanford University, 2014
    B.S. Mathematics, Massachusetts Institute of Technology, 2010

Current Status

  • Status: Postdoctoral Fellow
  • Research Area: Computational Biology
  • Contact Information: ikaplow@andrew.cmu.edu

Publications

Zhang X*, Kaplow IM*, Wirthlin M, Park TY, Pfenning AR. HALPER facilitates the identification of regulatory element orthologs across species. Bioinformatics, In Press.

Tycko J*, Wainberg M*, Marinov G*, Ursu O, Hess G, Ego B, Aradhana A, Li A, Truong A, Trevino A, Spees K, Yao D, Kaplow IM, Greenside P, Morgens D, Phanstiel D, Snyder M, Bintu L, Greenleaf W, Kundaje A, Bassik M. Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. Nature Communications, 10(1): 4063, 2019.

Tehranchi A, Hie B, Dacre M, Kaplow I, Pettie K, Combs P, Fraser HB. Fine-mapping cis-regulatory variants in diverse human populations. eLife, 8: e39595, 2019.

Kaplow IM, MacIsaac JL, Mah SM, McEwen LM, Kobor MS, Fraser HB. A pooling-based approach to mapping genetic variants associated with DNA methylation. Genome Research, 25(6): 907-917, 2015.

Dadiani M, van Dijk D, Segal B, Field Y, Ben-Artzi G, Raveh-Sadka T, Levo M, Kaplow I, Weinberger A, Segal E. Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise. Genome Research, 23(6): 966-976, 2013.

Kaplow IM*, Singh R*, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: Automated detection of significant genes from functional genomic screens. Nature Methods, 6(7): 476-477, 2009.

Schaub MA, Kaplow IM, Sirota M, Do CB, Butte AJ, Batzoglou S. A classifier-based approach to identify genetic similarities between diseases. Bioinformatics, 25(12): i21-29, 2009.

Awards

Carnegie Mellon Computational Biology Department Lane Postdoctoral Fellowship, awarded June 2017
Stanford Computational, Evolutionary, and Human Genomics Predoctoral Fellowship, awarded April 2015
National Science Foundation Graduate Research Fellowship, awarded April 2010 (deferred)
Stanford Graduate Fellowship, awarded April 2010 (deferred)
Anna Pogosyants Undergraduate Research Opportunities Program Award, awarded May 2008
Phi Beta Kappa honors society, initiated May 2010
Order of Omega honors society, initiated May 2009