Aleah Caulin

  • Program Years: 2010-2014
  • Academic Institution: University of Pennsylvania
  • Field of Study: Genomics and Computational Biology
  • Academic Advisor: Carlo Maley
  • Practicum(s):
    Lawrence Berkeley National Laboratory (2012)
  • Degree(s):
    B.S. Biology, Boston College, 2008
    PhD Genomics and Computational Biology, UPenn

Current Status

  • Status: Program Director of Preclinical Studies at PEEL Therapeutics
  • Research Area: Oncology
  • Publications

    Fox, Aleah K, Tuch, Brian B, Chuang, Jeffrey H. Measuring the prevalence of regional mutation rates: an analysis of silent substitutions in mammals, fungi, and insects. BMC Evolutionary Biology 2008, 8:186.

    Caulin, Aleah F and Maley, Carlo C. Peto's Paradox: Evolution's Prescription for Cancer Prevention. Trends in Ecology and Evolution, (2011) Vol 26 Issue 4, pp. 175-182.

    Benjamin Roche, Michael E. Hochberg, Aleah F. Caulin, Carlo C. Maley, Robert A. Gatenby, Dorothee Misse, Frederic Thomas. Natural resistance to cancers: a Darwinian hypothesis to explain Peto's paradox. BMC Cancer 2012, 12:387.

    Liu N, Caulin AF, Graham T, Jablons D, Maley CC. Within-tumor genetic diversity in lung cancer. Journal of the American College of Surgeons. 2012, 215(3), pp. S38.

    Caulin AF, Graham TA, Wang L-S, Maley CC. Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis. Philosophical Transactions of the Royal Society B: Biological Sciences. 2015;370(1673):20140222.

    Lisa M. Abegglen, Aleah F. Caulin, Ashley Chan, Kristy Lee, Rosann Robinson, Michael S. Campbell, Wendy K. Kiso, Dennis L. Schmitt, Peter J. Waddell, Srividya Bhaskara, et al. Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA. 2015 November 3; 314(17) doi: 10.1001/jama.2015.13134

    Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers
    Collin M. Blakely, Thomas B.K. Watkins, Wei Wu, Beatrice Gini, Jacob J. Chabon, Caroline E. McCoach, Nicholas McGranahan, Gareth A. Wilson, Nicolai J. Birkbak, Victor R. Olivas, Julia Rotow, Ashley Maynard, Victoria Wang, Matthew A. Gubens, Kimberly C. Banks, Richard B. Lanman, Aleah F. Caulin, John St. John, Anibal R. Cordero, Petros Giannikopoulos, Andrew D. Simmons, Philip C. Mack, David R. Gandara, Hatim Husain, Robert C. Doebele, Jonathan W. Riess, Maximilian Diehn, Charles Swanton, Trever G. Bivona
    Nat Genet. 2017 Dec; 49(12): 1693-1704. Published online 2017 Nov 6. doi: 10.1038/ng.3990

    Awards

    Excellence in Genome Science Frontiers Award 2008
    Cum laude May 2008
    Accepted to Honors Biology Program, Boston College, Sept 2007
    Society of Molecular Biology and Evolution Undergraduate Diversity Award 2007