Notable DOE CSGF alumna Amanda Randles models blood circulation — and is a role model for beginning scientists. Her Duke team continues to improve and expand the model’s biomedical uses, which include building digital twins, or computational copies, of patients’ circulatory systems and studying how metastasizing cancer cells travel through the bloodstream.
Amanda Randles is the Alfred Winborne and Victoria Stover Mordecai associate professor of biomedical sciences at Duke University. She developed HARVEY, a novel model for simulating blood flow during her Harvard University Ph.D. research, where she was a Department of Energy Computational Science Graduate Fellowship (DOE CSGF) recipient, with Efthimios Kaxiras and Hanspeter Pfister. She was one of the inaugural winners of the Sony Women in Technology Award with Nature in 2025 and has garnered numerous other honors, including a 2024 ISC Jack Dongarra Early Career Award and the 2023 ACM Prize in Computing. The interview, which also appears in the 2025 issue of DEIXIS: The DOE CSGF Annual, has been edited for clarity and length.