Formation of the Bicoid morphogen gradient in unfertilized Drosophila melanogaster eggs

Jeffrey Drocco, Princeton University


The Bicoid morphogen is a transcription factor which stands at the top of a genetic regulatory hierarchy controlling anterior-posterior pattern formation in dipteran embryos. We compare experimental measurements of Bicoid concentration in unfertilized D. melanogaster eggs to simulation to determine the likely means of establishment of the gradient.

Abstract Author(s): Jeffrey Drocco