Summary of Research
Modeling materials across scales endeavors to capture the causal continuum linking structural motifs to performance - a challenge that hinges on optimizing resolution against computational cost. At MIT CEE, I leverage in-silico techniques including molecular dynamics and physics-informed multiagent AI systems to explore these hierarchical relationships, designing and characterizing de novo materials engineered for extreme and dynamic environments.
Publications
1) Stewart, I., & Buehler, M. J. (2025). Molecular analysis and design using multimodal generative artificial intelligence via multi-agent modeling. Molecular Systems Design & Engineering, 10(2), 314-337.
2) Stewart, I., Garcia, M. J., Hedayatzadeh Razavi, A., Nafisi, N., Buzo, M., & Nazarian, A. (2024) Reducing variability in bone mechanical testing: A contactless bending approach for improved reproducibility [Accepted to Journal of Biomechanical Engineering.]
3) Stewart, I., Garcia, M. J., Alluri, N., Buzo, M., Keko, M., & Nazarian, A. (2024). A meta-analysis study to define variations in murine long bone biomechanical testing [Accepted to Journal of Biomechanical Engineering.]
4) Hedayatzadeh Razavi, A., Nafisi, N., Stewart, I., Et al. (2024). The biomechanical assessment of two stemless shoulder arthroplasty prostheses in uniformly poor-quality bone mineral density cadaveric specimens. Clinical Biomechanics, 120, 106346.
5) Williamson, P ., Garcia, M., Momenzadeh, K., Abbasian, M., Kheir , N., Stewart, I., Et al. (2023). A Validated Three-Dimensional, Heterogenous Finite Element Model of the Rotator Cuff and The Effects of Collagen Orientation. Annals of biomedical engineering, 51(5), 1002-1013.
6) Williamson, P . M., Yeritsyan, D., Peacock, T ., Chainani, P ., Momenzadeh, K., Asciutto, D., Pathirana, P ., Avakian, C., Stewart, I., Et al. (2023). A passive ankle dorsiflexion testing system to assess mechanobiological and structural response to cyclic loading in rat Achilles tendon. Journal of biomechanics, 156, 111664
7) Garcia, M., Caro, D., Buzo, M., Stewart, I., Rodriguez D., King E., Momenzadeh, K., Kheir , Nadim., Khak, M., Abbasian M., DeAngelis Joseph, Ramappa, A., Nazarian, Ara. Effect of Glenohumeral Abduction on Supraspinatus Tendon Strain: A Cadaveric Study. SurgiColl. 2024;2(3).
8) Stewart, I . (2023) Atomistic Modeling of Osseointegration: Binding Affinities and Modes for Therapeutic Proteins on Inorganic Surfaces. Wellesley College thesis repository (under embargo 2 years); [publication ready].
Posters:
1) Stewart, I., Buzo Mena, M., Garcia, M., & Nazarian, A. (2023, February). Influence of mouse femur positioning and orientation in 3-point bending framework: A finite element study [Poster presentation]. Orthopaedic Research Society Annual Meeting (ORS 2023), Dallas, TX, United States.
2) Stewart, I., Buzo Mena, M., Garcia, M., & Nazarian, A. (2023, October). High variabilities in mouse femur strength due to specimen malalignments and testing protocols [Poster presentation]. American Society for Bone and Mineral Research Annual Meeting (ASBMR 2023), Vancouver , BC, Canada.
Awards
- National Science Foundation (NSF) Graduate Research Fellowship - awarded Apr 2024
- MIT Whitaker Health Sciences Fellowship - awarded Mar 2025
- MIT GSO Fellowship - awarded Mar 2024
- Sigma Xi Honor Society (faculty nominated at Wellesley College) - awarded Dec 2023
- Beth Israel Deaconess Medical Center (BIDMC) Orthopedics Department Research Award - awarded Sep 2022