Modeling Cardiovascular Hemodynamics Using the Lattice Boltzmann Method on Massively Parallel Supercomputers

Amanda Peters Randles, Harvard University

Accurate and reliable modeling of cardiovascular hemodynamics has the potential to improve understanding of the localization and progression of heart diseases. However, building a detailed, realistic model of human blood flow is a formidable mathematical and computational challenge. The simulation must combine the motion of the fluid, the intricate geometry of the blood vessels, continual changes in flow and pressure driven by the heartbeat, and the behavior of suspended bodies such as red blood cells. Such simulations can provide insight into factors like endothelial shear stress that act as triggers for the complex biomechanical events that can lead to atherosclerotic pathologies. Currently, it is not possible to measure endothelial shear stress in vivo, making these simulations a crucial component to understanding and potentially predicting the progression of cardiovascular disease. In this talk, I will present and examine our approach for enabling an efficient parallel model of the fluid on both the IBM Blue Gene/P and Blue Gene/Q architectures and discuss the use of parallel-in-time decomposition to extend the number of time steps that can be modeled in a given wall-clock time.

Abstract Author(s): Amanda Peters Randles