- Program Year: 3
- Academic Institution: Michigan State University
- Field of Study: Chemistry
- Academic Advisor: Greg Severin
Lawrence Livermore National Laboratory (2019)
B.S. Chemistry, and B.S. Mathematics, Saint Mary's College, 2016
Summary of Research
My research project is to develop the techniques and strategies to collect and purify the most useful by-product radionuclides from the National Superconducting Cyclotron Laboratory (NSCL). These isotopes will be collected through a beam blocker system in which the unused radionuclides will accessible from the cooling water. In particular, my work will focus on harvesting 47Ca for the production of a generator to yield the medically relevant radioisotope 47Sc. The use of scandium isotopes in medical applications has become increasingly interesting as different isotopes can be used in complimentary pairs. Specifically, 43Sc and 44Sc can be used as positron emitters for PET and 47Sc can be used as an electron emitter for therapeutic treatments.
The ability to harvest these isotopes is made possible through the regular operation of the NSCL. Through projectile fragmentation, a primary beam is used to produce user specified secondary beams at the NSCL. While a single isotopic secondary beam of interest is used by the experimenters, the isotopes from unwanted secondary beams and unreacted primary beams are collected in beam stops and the cooling system along the beam line. Many of these leftover isotopes, such as 47Ca/47Sc, 48V, 88Zr, and 85Kr, are of interest for radiochemical studies. Current efforts at the NSCL are directed at making a beam blocker system to produce an aqueous mix of harvestable radioisotopes. In the future when FRIB comes online, a similar but larger scale system will be used to collect radionuclides of interest.
E. Paige Abel, Ken Moody, Narek Gharibyan
Production of Tungsten-188 with a Lithium-7 Irradiation of a Natural Tungsten Target for Applications in Nuclear Forensics
E. Paige Abel, Katharina Domnanich, Hannah Clause, Chirag Vyas, Colton Kalman, Wes Walker, Greg Severin
Using Isotope Harvesting Methods for the Generation of 47Sc and Radiolabeling of DTPA-TOC
E. Paige Abel*, Katharina Domnanich, Hannah Clause, Colton Kalman, Wes Walker, Greg Severin
Production, Collection, and Purification of 47Ca through Isotope Harvesting at the National Superconducting Cyclotron Laboratory
E. Paige Abel, Katharina Domnanich, Colton Kalman, Wes Walker, Jonathan W. Engle, Todd E. Barnhart, Greg Severin
Durability Test of a Flowing-Water Target for Isotope Harvesting
Accepted by Nuclear Instruments and Methods in Physics Research Section B in April 2020.
Katharina A. Domnanich, E. Paige Abel, Hannah Clause, Colton Kalman, Wesley Walker, Gregory W. Severin. An Isotope Harvesting Beam Blocker for the National Superconducting Cyclotron Laboratory. Nucl. Instrum. Methods Phys. Res. 2020, 959, 163526.
E. Paige Abel, Hannah Clause, and Greg Severin. Radiolysis and radionuclide production in a flowing-water target during fast 40Ca20+ irradiation. Appl. Radiat. Isotopes. 2020, 158, 109049.
E. P. Abel*, H. K. Clause, J. Fonslet, R. J. Nickles, and G. W. Severin. Half-lives of 132La and 135La. Phys. Rev. C. 2018, 97, 034312.
Mersedeh Saniepay*, Chenjia Mi, Zhihui Liu, E. Paige Abel and Remi Beaulac. Insights into the Structural Complexity of Colloidal CdSe Nanocrystal Surfaces: Correlating the Efficiency of on-Radiative Excited-State Processes to Specific Defects. J. Am. Chem. Soc. 2018, 140 (5), 1725-1736.
Emily P. Aldrich, Katherine A. Bussey, Jennifer R. Connell, Erin F. Reinhart, Kayode D. Oshin, Brandon Q. Mercado, and Allen G. Oliver. The Crystal Structure of Thermochromic bis-diethylammonium Tetrachlorocuprate Complexes. Acta Crystallographica E. Crystallographic Communications; January 2016.
MSU Graduate School Travel Grant, February 2020
Bursary Award for travel to the 17th Workshop on Targetry and Target Chemistry, August 2018
Department of Energy National Nuclear Security Administration Stewardship Science Graduate Fellowship (DOE NNSA SSGF), August 2017-present
National Superconducting Cyclotron Laboratory Graduate Fellowship, August 2016-2017
University Distinguished Fellowship from Michigan State University, August 2016-present
Chemistry Recruiting Fellowship from Michigan State University, August 2016-2017
Co-Valedictorian of the Class of 2016, Saint Mary's College, May 2016
Clare Booth Luce Scholarship for academic achievement in STEM, Saint Mary's College, August 2014-May 2016
Outstanding Student Award at the Nuclear Chemistry Summer School Brookhaven location, 2014
Induction into the Pi Mu Epsilon Mathematics Honor Society, Saint Mary's College, February 2014
NSF-PRISM Women's Scholarship for academic achievement in STEM, Saint Mary's College, August 2013-May 2014
Dean's List- 4.0 Honor Roll, Saint Mary's College, Every semester August 2012-May 2016
Vanguard Honors Program, Saint Mary's College, August 2012-May 2016
Moreau Presidential Scholarship, Saint Mary's College, August 2012-May 2014
Mother Pauline Award, Saint Mary's College, August 2012-May 2013