Abstract:

I extended a previous population genetic model of the selfish genetic element Medea to account for heterozygote killing and analyzed equilibrial stability. I then coupled the population genetic model with a set of ordinary differential equations describing the dynamics of a vector-borne disease like malaria. Feedback between the population genetic and epidemiological models is complicated by the fitness dependence of different mosquito genotypes on human disease prevalence. Implications for disease control are discussed.

Abstract Type
poster
Primary Author
Alex Perkins
University
University of California, Davis
Abstract Title
Application of selfish genetic elements to vector-borne disease control
Abstract Author(s)
Alex Perkins
Username
perkins
Fellowship Year
2007
First Name
Alex
Last Name
Perkins
Program
CSGF
Area of Study
Computational Biology
Poster Group
Group 1
Poster Number
27