Gavin Conant


University of New Mexico

Parallel Genehunter: Implementation of a Linkage Analysis Package
for Distributed-Memory Architectures

Abstract

We present a parallel algorithm for performing multipoint linkage analysis of genetic marker data on large family pedigrees. The algorithm effectively distributes both the computation and memory requirements of the analysis. We discuss an implementation of the algorithm in the Genehunter linkage analysis package (version 2.1), enabling Genehunter to be run on distributed memory platforms for the first time. Our preliminary benchmarks indicate reasonable scalability of the algorithm for even small fixed-size problems, with parallel efficiencies of 75% or more on up to a few dozen processors.

Gavin Conant*, Steve Plimpton†, William Old‡, Andreas Wagner*, Pam Fain‡, and Grant Heffelfinger†
*Department of Biology, The University of New Mexico
†Computation, Computers, and Mathematics Center, Sandia National Laboratories
‡Health Sciences Center, The University of Colorado

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